{"id":678160,"date":"2010-02-28T22:01:55","date_gmt":"2010-03-01T03:01:55","guid":{"rendered":"http:\/\/www.personalliberty.com\/liberty\/plant-derivative-may-reduce-resistance-to-breast-cancer-drug\/"},"modified":"2010-02-28T22:01:55","modified_gmt":"2010-03-01T03:01:55","slug":"plant-derivative-may-reduce-resistance-to-breast-cancer%c2%a0drug","status":"publish","type":"post","link":"https:\/\/mereja.com\/index\/678160","title":{"rendered":"Plant Derivative May Reduce Resistance To Breast Cancer\u00a0Drug"},"content":{"rendered":"<p><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/pictures.directnews.co.uk\/liveimages\/Breakthrough%2BBreast%2BCancer%2Bpink%2Bribbon%2Bbadge_1961_19624824_0_0_7043242_300.jpg?w=780\" alt=\"Plant derivative may reduce resistance to breast cancer drug \" align=\"right\" class=\"post_image\">A recent study has found that combining tamoxifen, the most prescribed breast cancer drug in the world, with a compound originating from the feverfew plant may help prevent initial or future resistance to the medication. <\/p>\n<p>&quot;A solution to tamoxifen resistance is sorely needed, and if a strategy like this can work, it would make a difference in our clinical care of breast cancer,&quot; said Robert Clarke, the study&#8217;s lead investigator.<\/p>\n<p>Approximately 70 percent of newly diagnosed breast cancer patients are prescribed tamoxifen, although half of those individuals do not initially respond to the drug due to an aggressive resistance. <\/p>\n<p>In the study, researchers from the Georgetown University Medical Center found that the purified chemical known as parthenolide, a derivative of feverfew, was able to successfully block the activity of nuclear factor kappa B (NF- \u03baB), a protein complex that is often over-expressed in breast cancer patients, leading to the body&#8217;s resistance to tamoxifen.<\/p>\n<p>Although the researchers are optimistic, they believe that it is too early to recommend the drug combination to patients as they are still unsure of its long-term benefits. <br \/><img data-recalc-dims=\"1\" decoding=\"async\" alt=\"ADNFCR-1961-ID-19624824-ADNFCR\" src=\"https:\/\/i0.wp.com\/feeds.directnews.co.uk\/feedtrack\/justcopyright.gif?w=780\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent study has found that combining tamoxifen, the most prescribed breast cancer drug in the world, with a compound originating from the feverfew plant may help prevent initial or future resistance to the medication. &quot;A solution to tamoxifen resistance is sorely needed, and if a strategy like this can work, it would make a [&hellip;]<\/p>\n","protected":false},"author":2670,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[4821],"tags":[],"class_list":["post-678160","post","type-post","status-publish","format-standard","hentry","category-news"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p9NivD-2Qq4","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/posts\/678160","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/users\/2670"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/comments?post=678160"}],"version-history":[{"count":0,"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/posts\/678160\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/media?parent=678160"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/categories?post=678160"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.com\/index\/wp-json\/wp\/v2\/tags?post=678160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}